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What are the limitations of RNAi screens?

What are the limitations of RNAi screens? - RNAi and SiRNA Forum

What are the limitations of RNAi screens? - Discuss and Post Questions in this forum about RNA interference and siRNA. RNAi and siRNA transfection, inhibition of endogenous genes, and miRNA and shRNA.


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Old 12-11-2012, 09:16 AM
Pipette Filler
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Default What are the limitations of RNAi screens?



Can expressing an RNAi against genes known to have an retinal degenerative mutant phenotype cause a retinal degenerative mutant phenotype?

Out of 13 genes confirmed to cause RD mutations, only 9 were confirmed through RNAi. Why were only 69% confirmed and not 100%
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