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RNAi and SiRNA Forum Discuss and Post Questions in this forum about RNA interference and siRNA. RNAi and siRNA transfection, inhibition of endogenous genes, and miRNA and shRNA.


RNAi Technology and p53!!?

RNAi Technology and p53!!? - RNAi and SiRNA Forum

RNAi Technology and p53!!? - Discuss and Post Questions in this forum about RNA interference and siRNA. RNAi and siRNA transfection, inhibition of endogenous genes, and miRNA and shRNA.


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Old 11-10-2011, 01:17 AM
Pipette Filler
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Default RNAi Technology and p53!!?



Hey guys!! Question about RNAi technology:
If there is a defect where p53 irreversibly binds to Mdm2 in murine cancer cells, how would you apply RNAi technology to resolve the issue (i.e. prevent the p53 and the Mdm2 gene interaction thereby release of the p53 for its tumor suppressor function)??
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