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| RNA Techniques Forum Post and discuss RNA methods and RNA science related topics. RNA extraction, cDNA synthesis, RNA EMSA, and other RNA protocols. |
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#1
01-03-2013, 12:00 AM
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 Antisense oligonucleotides (ASOs) and ss-siRNA Hi everyone Currently, single-stranded small interfering RNAs (ss-siRNAs) are used instead of double strand siRNA. In nucleotide sequence, the ss-siRNA is similar with antisense oligonucleotides (ASOs)??? Could you please explain what is difference between ASOs and ss-siRNAs? Alle  |
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#2
01-08-2013, 07:44 PM
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| Re: Antisense oligonucleotides (ASOs) and ss-siRNA An siRNA oligo uses RISC for its activity. An antisense oligo either activates RNase-H activity or sterically blocks its target. |
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| antisense , asos , oligonucleotides , ss-sirna , sssirna |
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