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Antisense oligonucleotides (ASOs) and ss-siRNA

Antisense oligonucleotides (ASOs) and ss-siRNA - RNA Techniques Forum

Antisense oligonucleotides (ASOs) and ss-siRNA - Post and discuss RNA methods and RNA science related topics. RNA extraction, cDNA synthesis, RNA EMSA, and other RNA protocols.


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Old 01-03-2013, 01:00 AM
Pipette Filler
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Default Antisense oligonucleotides (ASOs) and ss-siRNA



Hi everyone

Currently, single-stranded small interfering RNAs (ss-siRNAs) are used instead of double strand siRNA. In nucleotide sequence, the ss-siRNA is similar with antisense oligonucleotides (ASOs)??? Could you please explain what is difference between ASOs and ss-siRNAs?

Alle
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Old 01-08-2013, 08:44 PM
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Default Re: Antisense oligonucleotides (ASOs) and ss-siRNA

An siRNA oligo uses RISC for its activity. An antisense oligo either activates RNase-H activity or sterically blocks its target.
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antisense , asos , oligonucleotides , ss-sirna , sssirna


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