Antisense oligonucleotides (ASOs) and ss-siRNA
Currently, single-stranded small interfering RNAs (ss-siRNAs) are used instead of double strand siRNA. In nucleotide sequence, the ss-siRNA is similar with antisense oligonucleotides (ASOs)??? Could you please explain what is difference between ASOs and ss-siRNAs?
Re: Antisense oligonucleotides (ASOs) and ss-siRNA
An siRNA oligo uses RISC for its activity. An antisense oligo either activates RNase-H activity or sterically blocks its target.
|All times are GMT. The time now is 01:03 AM.|
Powered by vBulletin® Version 3.8.4
Copyright ©2000 - 2015, Jelsoft Enterprises Ltd.
Copyright 2005 - 2012 Molecular Station | All Rights Reserved