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Morpholinos and DMD: Skipping exon 23 in mdx mice ameliorates cellular pathologies

Morpholinos and DMD: Skipping exon 23 in mdx mice ameliorates cellular pathologies - RNA Techniques Forum

Morpholinos and DMD: Skipping exon 23 in mdx mice ameliorates cellular pathologies - Post and discuss RNA methods and RNA science related topics. RNA extraction, cDNA synthesis, RNA EMSA, and other RNA protocols.


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Old 01-12-2009, 07:34 PM
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Default Morpholinos and DMD: Skipping exon 23 in mdx mice ameliorates cellular pathologies



This is another step toward using Morpholino oligos as therapeutics for Duchenne muscular dystrophy.

Doran P, Wilton SD, Fletcher S, Ohlendieck K. Proteomic profiling of antisense-induced exon skipping reveals reversal of pathobiochemical abnormalities in dystrophic mdx diaphragm. Proteomics. 2009 Jan 8. [Epub ahead of print]

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ameliorates , cellular , dmd , exon , mdx , mdx mouse , mice , morphlino , morpholinos , pathologies , skipping


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