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Morpholinos and DMD: Skipping exon 23 in mdx mice ameliorates cellular pathologies
This is another step toward using Morpholino oligos as therapeutics for Duchenne muscular dystrophy.
Doran P, Wilton SD, Fletcher S, Ohlendieck K. Proteomic profiling of antisense-induced exon skipping reveals reversal of pathobiochemical abnormalities in dystrophic mdx diaphragm. Proteomics. 2009 Jan 8. [Epub ahead of print]
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|ameliorates , cellular , dmd , exon , mdx , mdx mouse , mice , morphlino , morpholinos , pathologies , skipping|