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rational siRNA design

rational siRNA design - Protocols and Methods Forum

rational siRNA design - Post Any Protocol, Method, Technique, Procedure or Tips / Troubleshooting for any Molecular Biology Technique.

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Old 04-07-2004, 12:13 AM
Chang Zhu
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Default rational siRNA design

SVM RNAi 3.6 --- Software for rational siRNA design

For more information, please visit [Only registered users see links. ]
Comments and suggestions welcome. Thanks.

1. Incorporates recent advances in rational siRNA
2. Selects siRNA target sequences based on simple
3. Learns from past successes and failures for
better siRNA design.
4. Automatically designs oligos for a variety of
technical platforms:
synthetic siRNA in vitro translated siRNA
shRNA vector-based siRNA
5. Tailors to user-specific systems.
6. Eliminates unintended targets by "Blast" search
transcribed genome sequences or predicted genes.
7. Avoids targeting to Single Nucleotide
Polymorphism (SNP) sites.
8. Generates scrambled controls.

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