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The transcriptome of a genome contains more components than the proteome.

The transcriptome of a genome contains more components than the proteome. - Proteomics Forum

The transcriptome of a genome contains more components than the proteome. - Post Questions and Discuss Proteomics, Proteomic Bioinformatics, Proteomic Techniques such as 2-D, Mass Spec etc.


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Old 05-25-2011, 02:16 AM
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Default The transcriptome of a genome contains more components than the proteome.



Explain why this is true.? The transcriptome of a genome contains more components than the proteome. Explain why this is true.
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Old 07-16-2011, 06:11 PM
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Default Re: The transcriptome of a genome contains more components than the proteome.

That statement may not necessarily be true.

All proteins are translated from mRNA and in addition to this there are many additional types of RNA that are not translated. So, it would at first glance appear that the transcriptome is more complex than the proteome, given that there are more RNA transcripts than primary proteins. However, proteins undergo a vast array of post-translational modifications. So any single protein might exist as a dozen or more different species.

So I think it would be very difficult to state that the transcriptome is more complex than the proteome because characterizing all protein isoforms in a cell would be extremely difficult.

It would be fair to argue that there are more RNA transcripts than there are primary proteins though.
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