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Post Questions and Discuss Proteomics, Proteomic Bioinformatics, Proteomic Techniques such as 2-D, Mass Spec etc.



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  #1 (permalink)  
Old 12-03-2007, 08:57 PM
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Wink For all SELDI-TOF-MS users
I would like to discuss with SELDI users some technical problems, please if someone have experience in this field, it would be great to discuss with him about this technology.
For exemple, does someone try to purify protein biomarker discovered by Seldi using the same technology ??
Please don't hesitate to reply, any suggestions could help me to get more idea.
thanks a lot
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  #2 (permalink)  
Old 12-03-2007, 09:01 PM
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Default Re: For all SELDI-TOF-MS users
We don't use SELDI anymore. It has a very bad reputation due to lousy resolution, reproducibility, reliability. I recommend you do not use SELDI-MS.
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Old 12-03-2007, 09:06 PM
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Default Re: For all SELDI-TOF-MS users
Check this out:
Bio-Rad tackles the 'SELDI biomarker controversy'
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Old 12-03-2007, 09:09 PM
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Default Re: For all SELDI-TOF-MS users
And this:
Reproducibility of SELDI-TOF protein patterns in serum: comparing datasets from different experiments -- Baggerly et al. 20 (5): 777 -- Bioinformatics
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