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conversion between units (ic50 <=> pKd)

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Old 06-28-2007, 01:36 PM
Pipette Filler
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Default conversion between units (ic50 <=> pKd)

hi

can anyone tell me how to convert from a given ic50 (half inhibitory concentration) to a Kd (dissociation constant) unit?
For example i have a MHC complex (HLA B*0801) with a peptide in the binding groove and i know that the ic50 value is around 359.0 for a given peptide FVRQCFNPM. whats the value of the (p)Kd?

thx
lordy
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