sorry if this is the wrong place to post! I was wondering if anyone would be able to shed any light on how I would be able to carry out preparative ultracentrifugation as a means to detect a protein-ligand interaction.
My supervisor wants me to find protocols or what-not that would allow me to spin a protein/drug mixed sample through some kind of gradient and then analyse the fractions to see if I can detect protein and/or drug.
Does anyone have any advice or help, I can't find anything solid on the web!!