Hydrophobic Protein Interactions

kiki06 · #1 (**permalink**) 01-10-2008, 01:55 PM

Hello,
does anyone know how to break hydrophobic interactions between two proteins?

What could I use to dismantle the bond?
thanks
Kiki

danfive · #2 (**permalink**) 01-10-2008, 09:24 PM

Use non-ionic or zwitterionic detergents or bile salts or maybe sulfobetaines.

bam pandit · #3 (**permalink**) 01-22-2008, 03:31 AM

anything that is more prone in getting the previous bonds to a lower energy level should help you get rid of the hydrophobic bonds you want to dismantle. the above substances mentioned by danfive are the popular ones.... but do go for a check regarding the quantities before getting to a conclusion.

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Hydrophobic Protein Interactions

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