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[Protein-analysis] scissile bond

[Protein-analysis] scissile bond - Protein Forum

[Protein-analysis] scissile bond - Protein Forum


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Old 12-04-2008, 08:36 PM
Mark Nance
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Default [Protein-analysis] scissile bond



Yogendra,

You can try Expasy's PeptideCutter:
[Only registered users see links. ]

The fold of the protein is important, because not all cleavage sites are accessible to proteases. Conformation is important, too. There are several protease protection assays where binding of protein / activation / etc. can be monitored by increases or decreases in susceptibility to specific proteases.

Mark


Hi all
Would any body help in letting us to know: how to identify scissile bonds in a protein sequence. Any web based tool or any triplet sequence related with Arg?

Thanks

Yogendra Sharma
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