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folding structure of this glycoprotein

folding structure of this glycoprotein - Protein Forum

folding structure of this glycoprotein - Protein Forum


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Old 06-12-2004, 12:05 PM
w2hgcg@netscape.net
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Default folding structure of this glycoprotein



I have not subscribe to this malling list, I have not found how to... so please mail me back directly and not just to the mailling list, thanks in advance.
I have four seuences (amino acid) of closely related genotypes in a viral complex. I need to predict the folding structure of this glycoprotein gene which is about 1640 amino acids long. I need to draw the 3D structure using the disulphide bonding with cyctine residues. I have the cleavage sites which have generated the two mature proteins. It is translated as a polyprotein and cleaved to genetate 2 mature proteins which are predicted to be glycosylated.
what I really want to know whether the changes in the AA sequence will alter the 3D structure os these strains compared to the base sequence structure. I have the sequence of the two prototype strains. any hints are more than wellcome... cheers

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