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Are thyrotropin releasing hormone (TRH) and Gonadotropin Releasing Hormong...

Are thyrotropin releasing hormone (TRH) and Gonadotropin Releasing Hormong... - Peptide Forum

Are thyrotropin releasing hormone (TRH) and Gonadotropin Releasing Hormong... - Peptide Forum. Ask and discuss questions on peptide protocols, custom peptide synthesis, peptide identification and peptide sequencing.


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Old 03-02-2013, 05:15 PM
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Default Are thyrotropin releasing hormone (TRH) and Gonadotropin Releasing Hormong...



...(GnRH) are small peptides? I'm pretty much confused differing small peptide. Are they less than 300 amino acids are considered "small peptides"? How many amino acids are they made from? Need help for this. Many thanks.
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Old 08-22-2013, 08:10 AM
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Thumbs up Re: Are thyrotropin releasing hormone (TRH) and Gonadotropin Releasing Hormong...

(GnRH) that is made of 10 amino acids

hyrotropin releasing hormone (TRH) :-it is synthesized as a 242-amino acid precursor polypeptide that contains 6 copies of the sequence -Glu-His-Pro-Gly-, flanked by di-basic peptides that are later processed through proteolysis to give the mature TRH molecule.

there is no fixed criteria but in-general

Amino acid :- Amino acids are molecules containing an amine group, a carboxylic acid group and a side-chain that varies between different amino acids NH2-CH(R)-COOH [ Where R is side chain).Their were 20 natural occuring amino acid and they are polymerize to give Peptide,Polypeptide and protein.

Peptide Bond :-A peptide bond is a covalent bond that is formed between two amino acid when the carboxyl group of one amino acid reacts with the amino group of the another amino acid. Simply [O=C-NH ], while amide bond is [O=C-NH2]

Peptide :- Peptides are short polymers of amino acids linked by peptide bonds. Here is confusion about no. of amino acid but mostly till 50 amino acid they were called peptide or polypeptide and if no. of amino acid is more then 50 it's called protien.

Polypeptide is same as peptide which use by some of the chemist to define peptide haviny amino acid more then 2 but less then 50 .

Protein :- Having amino acid more then 50 which were linked by peptide bond
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Old 08-22-2013, 01:49 PM
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Default Re: Are thyrotropin releasing hormone (TRH) and Gonadotropin Releasing Hormong...

All proteins are peptides (or formed by peptides), but not all peptides are proteins. It goes far beyond the number of aminoacids.

Let's take hemoglobin for example. Alpha and beta subunits by themselves are peptides (or polypeptides) but they are not considered proteins. The joining of two alpha and two beta subunits plus the addition of iron form the functional hemoglobin. So, hemoglobin is a protein formed by four polypeptides plus iron.

Considering all this I may say protein are called like that based on functionality more than in structure.
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gonadotropin , hormone , hormong , releasing , thyrotropin , trh


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