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Fire 09-30-2012 05:16 PM

Given the sequence of the following peptide?
 
Given the sequence of the following peptide: I L W A N R M S H V L F A V E A
which amino acid residues would you expect to be on the solvent-exposed surface once it folds into its native conformation? There is more than one correct amino acid. Select all that apply.

5 of the amino acids must be chosen.
Please help!!!

Kunal Pandya 10-01-2012 04:01 AM

Re: Given the sequence of the following peptide?
 
I L W A N R M S H V L F A V E A

N (Asparagine ) R(Arginine) E (Glutamic Acid) (Higly hydrophilic amino acid so It would expect to be on the solvent-exposed surface

S (Serine) H (Histidine) This two also having hydrophilic nature but not as much as above three but it also expect to be on the solvent-exposed surface

I L W A M V L F are hydrophobic residue thus they buried inside the protein and thus shielded from the solvent


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