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How to draw the structural formula to amino acid peptide?

How to draw the structural formula to amino acid peptide? - Peptide Forum

How to draw the structural formula to amino acid peptide? - Peptide Forum. Ask and discuss questions on peptide protocols, custom peptide synthesis, peptide identification and peptide sequencing.


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Old 12-19-2011, 10:18 PM
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Default How to draw the structural formula to amino acid peptide?



I'm confused by what my microbiology teacher wants me to do with the following problem:
"Consider the following peptide:
lysine-valine-threonine-
cysteine-leucine-proline-
gluamine-glutamic acid-aspartic acid-tryptophan, with lysine as the amino-terminal acid and tryptophan as the carboxy-terminal amino acid in the peptide.

Draw out the complete structural formula of the peptide and determine the overall ionic charge on the peptide at pH 7.0. Charge at acid pHs? Charge at alkaline pHs?"

Can someone help me figure out how to draw this structure and figure out the ionic charges?
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Old 12-20-2011, 08:57 AM
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Smile Re: How to draw the structural formula to amino acid peptide?

Ionic charge at acidic pH 2~3

Lys-Val-Thr-Cys-Leu-Pro-Gln-Glu-Asp-Trp
+2 + 0 + 0 + 0 + 0 + 0 + 0 +0 + 0 (-1) = + 1

Ionic charge at acidic pH 5~6

Lys-Val-Thr-Cys-Leu-Pro-Gln-Glu-Asp-Trp
+2 + 0 + 0 + 0 + 0 + 0 + 0+(-1)+(-1)+(-1) = -1

Ionic charge at neutral pH 7

Lys-Val-Thr-Cys-Leu-Pro-Gln-Glu-Asp-Trp
+2 + 0 + 0 + 0 + 0 + 0 + 0+(-1)+(-1)+(-1) = -1
Ionic charge at basic pH 12

Lys-Val-Thr-Cys-Leu-Pro-Gln-Glu-Asp-Trp
0 + 0 + 0+(-1)+ 0 + 0 + 0 +(-1)+(-1)+(-1) = -4

Regards
Kunal Pandya
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