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how to calculate peptide bonds in the exercise below?

how to calculate peptide bonds in the exercise below? - Peptide Forum

how to calculate peptide bonds in the exercise below? - Peptide Forum. Ask and discuss questions on peptide protocols, custom peptide synthesis, peptide identification and peptide sequencing.


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Old 11-21-2011, 04:15 AM
Pipette Filler
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Default how to calculate peptide bonds in the exercise below?



A protein consists of 480 amino acids. How many peptide bonds are needed to link those amino acids? How many water molecules are released from this protein synthesis?
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Old 11-21-2011, 04:15 AM
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479 and 479



Start off with the simplest example: a dipeptide.
A-A
If there are 2 amino acids linked together, then there is only 1 peptide bond between them.

Try a tripeptide.
A-A-A
If there are 3 amino acids, then there are 2 peptide bonds between them.

The general logic holds for higher numbers. That is, the number of peptide bonds is 1 less than the number of amino acids.

So with 480 amino acids, there would be 479 peptide bonds.



One molecule of water is released for each peptide bond formed. There are 479 peptide bonds formed, so 479 molecules of water are released.
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