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cleavage of the trityl group

cleavage of the trityl group - Peptide Forum

cleavage of the trityl group - Peptide Forum. Ask and discuss questions on peptide protocols, custom peptide synthesis, peptide identification and peptide sequencing.


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Old 11-04-2009, 04:40 PM
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Default cleavage of the trityl group



hi,
how can I cleave the trityl group from cysteine containing peptides. I used TFA/TES/DCM but did not work well. is necessary to use EDT?
thanks in advance
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Old 02-26-2011, 10:17 PM
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Default Re: cleavage of the trityl group

I think it's standard to include EDT or DODT when having Cys, Trp or Met in a sequence. You might wanna use TIPS instead of TES.

\Erik
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