Science Forums Biology Forum Molecular Biology Forum Physics Chemistry Forum

Science Forums Biology Forum Molecular Biology Forum Physics Chemistry Forum (http://www.molecularstation.com/forum/)
-   Peptide Forum (http://www.molecularstation.com/forum/peptide-forum/)
-   -   resins for peptide synthesis. (http://www.molecularstation.com/forum/peptide-forum/66982-resins-peptide-synthesis.html)

desvila 06-18-2009 01:58 AM

resins for peptide synthesis.
 
I need to know what is the criteria for the selection of a particular type of resins for peptide synthesis. I am focussing on synthesis on peptides for cosmetic applications. What kind of resins would be best for me, since I am doing this for the first time.

beike 07-12-2009 11:26 AM

Re: resins for peptide synthesis.
 
This depend on the peptide you want to synthesize, especially the first amino acid in the C-terminal, in our lad, we usually use Wang-resine if the first amino acids in C-terminal are a Ala, Arg, Asn, Asp, Glu, Gln, Gly, His, Ile, Leu, Lys, Met, Phe, Ser, Thr, Trp, Tyr and Val; and merrifield cl resin if is Pro, Cys. MBHA or AM resin if is conh.

Hope this would be help.
Good luck

gazlinteb 09-14-2009 01:21 PM

Re: resins for peptide synthesis.
 
Does someone have a protocol to synthesis a cyclic peptide? what is a preferred resin for this propose?

glbiochem 09-16-2009 03:25 AM

Re: resins for peptide synthesis.
 
Wang Resin is cheapest for C terminus acid, Rink Amide AM Resin is cheapest for C terminus amine.
As the cosmetic peptides are very short. The high loading is prefered.


All times are GMT. The time now is 05:00 AM.

Powered by vBulletin® Version 3.8.4
Copyright ©2000 - 2014, Jelsoft Enterprises Ltd.
Copyright 2005 - 2012 Molecular Station | All Rights Reserved

Page generated in 0.08989 seconds with 11 queries