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How to check peptide aggregation in solution?
I would like to know whether my peptide exists as a monomer or dimer, or aggregates in aqueous solution. Can anyone suggest reliable ways to confirm it? Many thanks in advance.
Re: How to check peptide aggregation in solution?
Do an HPLC and confirm it with maldi or esi. If the maldi gives you a single peak but your hplc shows you 2 or more peaks, that means your peptide is aggregating. Sequence of u r peptides also helps us to predict aggregation.
|aggregation , check , monomer , peptide , solution|
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