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-ssRNA viruses

-ssRNA viruses - Omics and Genomics Forum

-ssRNA viruses - Discuss and post questions about Genomics, Proteomics, Drug discovery, and Interactome research.


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  #1  
Old 11-04-2006, 10:15 AM
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Default -ssRNA viruses



Hi
i want to know about the negative single stranded RNA viruses, that how these viruse replicate in the host, as negative sence single stranded RNA does not encode any message directly and it has to convert into +sence RNA, so how this conversion occurs in the host?

aftab
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Old 11-05-2006, 09:33 PM
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Default Re: -ssRNA viruses

Hello Aftab!
This is a very interesting question as I have studied Virology.

This involves reverse transcriptase if I remember correctly which translates the sequence into + strand for proper expression.

We should post a detailed mechanism here.
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Old 11-07-2006, 04:32 PM
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Default Re: -ssRNA viruses

Hi
but i think there is RNA dependent RNA polymerase enzyme that is present in the virus which converts the negative sence ssRNA strand into positive sense ssRNA, and then this is translated direclty.
as we know that the purpose of reverse transcriptase is to convert the RNA into DNA so it is not involved in this conversion.
need more comments.......


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aftab
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