Metabolomics

[molecule2005]

what is Metabolomics and how is used in research and medicine?

thanks

[aftabac]

Hi
following paragraph give a brief introduction of metabolomics and its importance.

Metabolomics is a newborn cousin to genomics and proteomics. Specifically, metabolomics involves the rapid, high throughput characterization of the small molecule metabolites found in an organism. Since the metabolome is closely tied to the genotype of an organism, its physiology and its environment (what the organism eats or breathes), metabolomics offers a unique opportunity to look at genotype-phenotype as well as genotype-envirotype relationships. Metabolomics is increasingly being used in a variety of health applications including pharmacology, pre-clinical drug trials, toxicology, transplant monitoring, newborn screening and clinical chemistry. However, a key limitation to metabolomics is the fact that the human metabolome is not at all well characterized.
Unlike the situation in genomics, where the human genome is now fully sequenced and freely accessible, metabolomics is not nearly as developed. It is estimated that only a quarter to half of endogenous human metabolites in blood or urine have been positively identified. Of those that have been identified, very few have any information on their normal concentration ranges.


regards
aftab

[kmunson779]

Metabolomics sounds like an eating disorder to me! It's pretty amazing how many new "ome" terms have been recently created... and it'll be interesting to see how many of them actually stick around and produce something useful and/or interesting!

[kiki06]

Wow. Science is supposed to simplify things.

I think things are getting very complex now with our current understanding of nature.