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Development of Fluorescent Probes

Development of Fluorescent Probes - Molecular Biology Techniques

Development of Fluorescent Probes - Molecular Biology Forum. Includes forums for common molecular biology techniques.


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Old 09-04-2009, 09:12 AM
Pipette Filler
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Default Development of Fluorescent Probes



OTAVA Ltd. is among leading companies conducting research in the area of designing novel, highly efficient fluorescent probes for biology and medicine. Years of experience enables us to participate in a number of contract research projects with European and American companies.

Our company proposed an original and pioneering approach to design fluorescent probes with required properties. It is called "lead dye" method that makes the discovery process faster and a positive result is more predictable. It is based on our proprietary in-stock collection of about 2,000 dyes of various classes.

Our prolific team-work with Sigma-Aldrich resulted in production of novel high-sensitive series of fluorescent dyes (LUCY) for nonspecific detection of proteins in gels:
[Only registered users see links. ]
Using our distinctive “lead dye” method OTAVA and Sigma-Aldrich jointly released novel fluorescent stain Nancy-520 for dsDNA visualization on agarose gels:
[Only registered users see links. ]

In collaboration with BioRad, Inc. we also elaborated novel long-wavelength fluorescent probes for unspecific detection of proteins in separation systems.

Based on our company’s continuing devotion to developing long-wavelength dyes for DNA detection, specific and non-specific protein detection, fluorescent dyes for labeling of biomolecules, we offer to all interested parties to collaborate in these fields.

For more details, please visit our website
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Old 09-23-2009, 10:22 AM
Pipette Filler
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Default Re: Development of Fluorescent Probes

I'm going nuts trying to figure out if you calculate the Mean Squared Displacement of a group of particles at time t by taking the average of the squares of their displacements at time t from their initial positions or by taking the average of the squares of their cumulative displacements at time t. Does anyone understand what I mean? For example, one particle may move a cumulative distance of 500 nm in a second, but it may end up only 10 nm from where it started. Would you take the square of 500 or the square of 10??
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