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dsRNA viruses and RNAi

dsRNA viruses and RNAi - Microbiology Forum

dsRNA viruses and RNAi - Discuss Microbiology Science and Protocols here. Post questions on the study of viruses, fungi, parasites and bacteria here. Microbiology Forum.


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Old 11-06-2006, 02:56 PM
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Question dsRNA viruses and RNAi



Hi
as we know that DICER enzyme act on dsRNA and make it siRNA by breaking it, i want to know why Dicer did not cut the dsRNA viruses as we know that they are lot of examples of dsRNA viruses and how they replicate inside the host that have dicer in it to cut the dsRNA.



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aftab ahmad
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Old 11-06-2006, 05:57 PM
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Default Re: dsRNA viruses and RNAi

One model says that Dicer and the RNAi machinery may have evolved in order to combat dsRNA viruses, so the viruses, in turn, have been evolving to foil Dicer. See, for example, [Only registered users see links. ] in Nature Structural & Molecular Biology, and the [Only registered users see links. ]. Google brought up a bunch more.
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