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Plus and Minus strands of viruses

Plus and Minus strands of viruses - Microbiology Forum

Plus and Minus strands of viruses - Discuss Microbiology Science and Protocols here. Post questions on the study of viruses, fungi, parasites and bacteria here. Microbiology Forum.


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Old 04-09-2008, 07:25 AM
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Default Plus and Minus strands of viruses



Hi
What is basis of classification of plus and minus strands in Viruses?



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aftab
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Old 04-09-2008, 02:37 PM
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Cool Re: Plus and Minus strands of viruses

Hello Aftab,

For viruses that contain RNA as coding nucleic acid, the strands are said to be either positive-sense (+ or also called plus-strand) or negative-sense (- or also called minus-strand).

The naming is dependent on whether it is complementary to viral mRNA.


Positive-sense (+) viral RNA is identical to viral mRNA and thus can be immediately translated by the host cell.

Negative-sense (-) viral RNA is complementary to mRNA and must be first converted to positive-sense RNA by an RNA polymerase before translation.

DNA viral strand nomenclature is similar to RNA nomenclature, in that the coding strand for the viral mRNA is complementary to it (-), and the non-coding strand is a copy of it (+).

Hope this helps
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Old 04-27-2008, 10:32 AM
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Default Re: Plus and Minus strands of viruses

Hi
thanks for this elaborate answer. Hopefully this will help many other researchers.


regards
aftab
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