Go Back   Science Forums Biology Forum Molecular Biology Forum Physics Chemistry Forum > Molecular Research Topics Forum > Animal and Molecular Model Systems > Microbiology Forum
Register Search Today's Posts Mark Forums Read

Microbiology Forum Discuss Microbiology Science and Protocols here. Post questions on the study of viruses, fungi, parasites and bacteria here. Microbiology Forum.


Citric Acid Cycle

Citric Acid Cycle - Microbiology Forum

Citric Acid Cycle - Discuss Microbiology Science and Protocols here. Post questions on the study of viruses, fungi, parasites and bacteria here. Microbiology Forum.


Reply
 
LinkBack Thread Tools Display Modes
  #1  
Old 10-11-2005, 12:29 AM
Sweets
Guest
 
Posts: n/a
Default Citric Acid Cycle



Citric Acid Cycle

Also know as the Krebs Cycle
The citric acid cycle completes the energy yielding oxidation of orgainic molecules
If molecular oxygen is present, pyruvate enters the mitochondrion. Here the enzymes of the krebs cycle complete the oxidation of the organic fuel. As the pyruvate enters the mitochondrion through the active transport, it is converted to a compound known as acetyl coenzyme (acetyl CoA).

Process Overview

1.. Acetyl CoA adds its 2-carbon acetyl group to oxaloacetate, which produces citrate.
2.. By the removal of a water molecule and addition of another, citrate is converted into isocitrate.
3.. Citrate losses a CO2, the result looses an electron, reducing NAD+ to NADH.
4.. Another CO2 is lost, and the result is again oxidized reducing NAD+ to NADH. The remaining molecule next attached to CoA by an unstable bond.
5.. CoA is then displaced by a phosphate group, which is transferred to GDP, forming GTP and then to ATP, this is by substrate-level phosphorylation, (process in which ATP is made by enzyme transfer of a phosphate group from an organic substrate to ATP.)
6.. Two hydrogens are transferred to FAD, forming FADH2 and oxidizing succinate.
7.. The addition of a H2O rearranges bonds in the substrate. The substrate is oxidized reducing NAD+ to NADH and regenerating oxloacetate.
Reply With Quote
Reply

Tags
acid , citric , cycle


Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Trackbacks are On
Pingbacks are On
Refbacks are On

Forum Jump

Similar Threads
Thread Thread Starter Forum Replies Last Post
What is Citric Acid? laura010 Chemistry Forum 8 12-16-2011 11:07 AM
10 mM HCl for IGF-I low.d Chemistry Forum 19 01-22-2010 12:33 AM
What'll happen if add extra 8 acid in TCA cycle?? astcws Biochemistry Forum 1 03-14-2009 12:34 AM
Deposizione rame su tubi in alluminio Max83 Forum Chimica 18 01-12-2008 05:48 PM
Acetic vs citric acid JEDilworth Microbiology Forum 1 03-20-2006 09:17 PM


All times are GMT. The time now is 01:36 PM.


Powered by vBulletin® Version 3.8.4
Copyright ©2000 - 2014, Jelsoft Enterprises Ltd.
Copyright 2005 - 2012 Molecular Station | All Rights Reserved
Page generated in 0.11256 seconds with 16 queries