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Why is Streptomycin less effective against gram-positive bacteria?

Why is Streptomycin less effective against gram-positive bacteria? - Microbiology Forum

Why is Streptomycin less effective against gram-positive bacteria? - Discuss Microbiology Science and Protocols here. Post questions on the study of viruses, fungi, parasites and bacteria here. Microbiology Forum.


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Old 04-13-2005, 07:48 PM
Jenny Gibbs
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Default Why is Streptomycin less effective against gram-positive bacteria?



I'm an A-Level Biology student and am in the middle of a Microbiology
coursework.

I had to research and compare the effectiveness of Streptomycin against a
gram positive (Staphylococcus albus) and a gram-negative (E.coli) bacteria.
I found that Streptomycin was significantly more effective against the
gram-negative strain, a pattern supported by background research. I know
that Streptomycin works by inhibiting protein synthesis but can't see why
this would be more effective against gram negatives than gram positives,
particularly given the fact that gram-negatives have the second outer
membrane to inhibit the entry of chemicals into a cell.
Can anyone help please?
I will make due reference to any help in the Bibliography section of the
coursework.
Many thanks.
Jenny


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Old 04-14-2005, 02:31 AM
Larry D. Farrell
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Default Why is Streptomycin less effective against gram-positive bacteria?

This exact question has just been addressed in sci.bio.microbiology.

Jenny Gibbs wrote:

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bacteria , effective , grampositive , streptomycin


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