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| i got this from one of my mailing lists.... This month, we bring you news of five new titles on metabolic engineering, expression technology, malaria, RT-PCR, and prions. ************************************************** ************************** ****************************************** METABOLIC ENGINEERING IN THE POST GENOMIC ERA Editors: Boris N. Kholodenko and Hans V. Westerhoff of the Thomas Jefferson University, Philadelphia USA and BioCentrum Amsterdam, The Netherlands Publisher: Horizon Bioscience ISBN: 0-9545232-2-9 Publication date: 01 January 2004 (Available now!!!) Price: GB£ 90 US$180 Pages: ix plus 456 Description: This book aims to help the reader understand and deal with the plasticity of living cell factories and to turn the plasticity into the desired rather than the adverse direction. The book brings together all the recent, most important breakthroughs in this exciting field. Internationally renowned scientists review each topic in detail. The editors provide an overview of new approaches and describe what the engineer and the industry may now aim for, even adapting the definition of metabolic engineering to befit the post-genomics era. Other topics covered: the experimental approaches necessary to understand cellular regulation at all of its hierarchical levels, including proteomics, metabolomics and fluxomics; new tools that help metabolic engineering; modeling of living cells; and the optimization of cell factories as production organisms. A useful chapter on future perspectives directs further developments of the field in the near future. Essential reading for everyone with an interest in engineering living cells including: Metabolic engineers, geneticists, microbiologists, bioengineers, biotechnologists, molecular and system biologists, and pharmaceutical and biotechnology companies. [Only registered users see links. ] ************************************************** ************************** ****************************************** PROTEIN EXPRESSION TECHNOLOGIES: CURRENT STATUS AND FUTURE TRENDS Editor: François Baneyx of the Department of Chemical Engineering University of Washington, Box 351750, Seattle, WA 98195, USA Publisher: Horizon Bioscience ISBN: 0-9545232-5-3 Publication date: April 01, 2004 Price: GB£ 90 US$180 Pages: c. x + 534 Description: Advances in protein expression technologies have mushroomed in recent years. In this book internationally renown authors comprehensively review current and emerging expression technologies. Detailed reviews of the molecular genetics of expression systems in various organisms are presented. Topics covered include: Expression of extremophilic proteins; expression in E. coli, Bacillus spp., Saccharomyces cerevisiae, and methylotrophic yeasts; insect cell expression and the baculovirus system; and Chinese Hamster Ovary (CHO) cell lines for large-scale protein production. Also covered are two emerging expression systems, Methylobacterium extorquens AM1 and Caulobacter crescentus. An essential reference, this book will enable both new and experienced expression technologists to make educated choices on the technology that is best suited for their needs. [Only registered users see links. ] ************************************************** ************************** ****************************************** MALARIA PARASITES: GENOMES AND MOLECULAR BIOLOGY Editors: Andrew P. Water and Chris J. Janse of Leiden University Medical Centre, Leiden, The Netherlands. Publisher: Caister Academic Press ISBN: 0-9542464-6-2 Publication date: March 01, 2004 Price: GB £115 US $230 Pages: c. 500 Description: The completion of the Plasmodium falciparum genome sequence in late 2002 hearlded a new era in malaria research. The search began in earnest for new drugs and vaccines to combat malaria, a disease which afflicts up to 500 million people worldwide and is responsible for the deaths of more than one million people each year. The new genomic data is aiding a greater understanding of the living parasite and it's interaction with the insect vector and human host. In this book internationally renown experts provide up-to-date reviews of the most important aspects of post-genomic malaria research. Topics covered include: the P. falciparum genome and model parasites, bioinformatics and genome databases, microsatellite analysis, analysis of chromosome structure, cell cycle to RNA polymerase I and II mediated gene expression, role of the nuclear genome, the parasite surface and cell biology, and much more. The book is essential to all researchers working in this highly topical field and is recommended reading for scientists in other areas of biology and medicine. [Only registered users see links. ] ************************************************** ************************** ****************************************** ADVANCE NOTICE: TWO TITLES COMING SOON!!! PRIONS AND PRION DISEASES: CURRENT PERSPECTIVES Editor: Glenn C. Telling In recent years, research into prions and prion diseases has progressed at an impressive pace. In this book internationally renown experts provide an up to date description of the great advances made in our understanding of prions and prion diseases in recent years. This volume provides a comprehesive overview of the pathogenesis, molecular biology, biochemistry, cellular biology, animal models and immunology of prions and follows from and expands on our highly acclaimed book "Prions: Molecular and Cellular Biology". The book is essential to all researchers working in this highly topical field and is recommended reading for scientists in other areas of biology and medicine. Coming soon!!! [Only registered users see links. ] REAL-TIME PCR: AN ESSENTIAL GUIDE Editors: Julie Logan, Kirstin Edwards and Nick Saunders Real-time PCR is a powerful and rapid technique for nucleic acid amplification. The accumulation of specific products in a reaction is monitored continuously during cycling. This is usually achieved by monitoring changes in fluorescence within the PCR tube. This essential manual presents a comprehensive guide to the most appropriate and up-to-date technologies and applications as well as providing an overview of the theory of this important technique. Written by recognized experts in the field this timely and authoritative volume is an essential requirement for all laboratories using PCR. Topics covered include: Real-time PCR technology and instruments, methods and techniques, controls and validation, quantitative real-time PCR, analysis of mRNA expression, mutation detection, NASBA, application in clinical microbiology and diagnosis of infection. Coming soon!!! [Only registered users see links. ] |
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