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| Free Software for DNA and Protein Microarrays: AFM (Array File Maker) - Samuel Lunenfeld Research Institute, Mount Sinai Hospital (Toronto) Software AMADA (Analyzing Microarray Data) - Univ of Hong Kong http://web.hku.hk/~xxia/software/AMADA.htm ANOVA programs for microarray data - Churchill's group at Jackson Lab http://www.jax.org/research/churchil...ova/index.html ANOVARRAY - SAS macros AnovArray — MIG BABELOMICS - Centro de Investigacion Principe Felipe, Spain www.babelomics.org CHIPINFO (retrieving annotation information from NetAffx and Gene Ontology): - Wong's lab at Harvard Univ ChipInfo CLUSFAVOR (CLUSter and Factor Analysis using Varimax Orthogonal Rotation), - Baylor http://mbcr.bcm.tmc.edu/genepi/ CLUSTER, TREEVIEW: - Eisen's lab at Lawrence Berkeley National Lab EisenLab also, http://www.microarrays.org/software.html CYBER-T - web interface for t-test, regularized t-test, etc. Welcome to Cyber-T CYTOSCAPE : visualizing molecular interaction networks and integrating these interactions with gene expression profiles and other state data. Cytoscape: Analyzing and Visualizing Network Data D-CHIP: specifically for Affymetrix chip data - Wong lab at Biostatistics Department, Harvard University dChip DNC-MIX: models the distribution of the gene expression profile as a mixture, - Lin group at Ohio State University DNC_MIX GENE@WORK : IBM Research IBM Research | Projects | Functional Genomics and Systems Biology - Automatic Redirection GENE-CLUSTER: Whitehead Institute (registration is required). Commercial version at Affymetrix http://www.genome.wi.mit.edu/MPR/software.html GENE-PATTERN : Broad Institute. GenePattern GEDA: gene expression data analysis. Univ Pittsburg caGEDA: A web application for the integrated analysis of global gene expression patterns in cancer GEDS: gene expression data simulator - University of Pittsburg http://www.contentsoft.de/index.htm?geneviz.htm GEPAS : gene expression pattern analysis suite - Centro de Investigacion Principe Felipe, Spain www.gepas.org GOSURFER - Wong lab at Harvard University GoSurfer J-EXPRESS - University of Bergen, Norway J-Express MAANOVA - Jackson Lab, MAANOVA 2.0 - The Jackson Laboratory ONTO-EXPRESS - Wayne Univ Intelligent Systems and Bioinformatics Laboratory PAGE (PAtterns from Gene Expression) - Univ. Penn. PaGE - Patters from Gene Expression PLAID - Owen lab at Stanford Univ. Plaid models for dna microarray data R_SVM (recursive sample classification by SVM) - Wong lab at Harvard Univ http://biosun1.harvard.edu/~xzhang/R-SVM/R-SVM.html SAM (significance analysis of microarrays) - Tibshirani's group at Stanford Univ. Significance Analysis of Microarrays SAM (significance of array measurement) - Institute for Systems Biology Institute for Systems Biology: Home SMA (Statistic for Microarray Analysis, in R or S-PLUS subroutines) - Speed's lab at Statistics Department of UC Berkeley R package: Statistics for Microarray Analysis (SMA) STEM (short time-series expression miner): from Carnegie Mellon Univ STEM: Short Time-series Expression Miner SVDMAN: from Los Alamos National Laboratory http://public.lanl.gov/mewall/svdman/ TREE-ARRANGE and TREEPS : from Univ Waterloo Bioinformatics Research at the University of Waterloo VERA (variability and error assessment) - Institute for Systems Biology Institute for Systems Biology: Home XCLUSTER - Sherlock's lab of Genetics Department of Stanford Univ Clustering Program Please post your reviews of this microarray software below. Cheers! Moleculardude |
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| The software list is impressive. I only used SAM. If you want to analyse replicates of the same experiment SAM can do the job. You can get genes that are significantly up or downregulated across your replicates. You will also get the average fold changes for significant genes. The problem I had with SAM is that I had groups of replicates with common control. I wanted the fold difference between groups of replicates, not within the group. Sam could not do this. I used ANOVA for this but it gives you significantly different genes between groups, without fold changes. I am still struggling with this. I also used mev4 (TIGR) software. It is very good for freeware. |
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| The software list is impressive. I only used SAM from this list. If you want to analyse replicates of the same experiment SAM can do the job. You can get genes that are significantly up or downregulated across your replicates. You will also get the average fold changes for significant genes. The problem I had with SAM is that I had groups of replicates with common control. I wanted the fold difference between groups of replicates, not within the group. Sam could not do this. I used ANOVA for this but it gives you significantly different genes between groups, without fold changes. I am still struggling with this. I also used mev4 (TIGR) software. It is very good for freeware. My favorit is still Genespring. What you pay is what you get. |
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