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Molecular weight calculation of Herceptin

Molecular weight calculation of Herceptin - Mass Spectrometry Forum

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Old 09-07-2012, 07:40 AM
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Question Molecular weight calculation of Herceptin



Hi Everybody,

The molecular weight of herceptin is 148 kDa. Can anyone enlighten me on how the molecular weight is being calculated ?

I tried used GPMAW, input the light and heavy chain sequence to calculate the mass of Herceptin. I even added N-glycosylation, but am still unable to obtain 148kDa. Please kindly explain and help!

Thank you!
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calculation , herceptin , intact ms , lcms , molecular , molecular weight , weight


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