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| Hey, Has anyone performed any dopamine detection work before? I'm developing a method for detecting dopamine using an LC-MS/MS QSTAR setup. I have been employing a HILIC column for chromatography, 10mM Ammonium acetate or formate in buffer A, 0.1% formic acid in acetonitrile in buffer B, a gradient from 90%B to 20%B, scans targeting a parent ion of m/z 154 and diagnostic fragment of m/z 91. The results have been... varied. Any suggestions, comments, jokes to brighten my day would be greatly appreciated. Thanking you in advance, Brendan. |
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| detection , developing , dopamine , lc-ms/ms , lcms or ms , mass spec , method , method development , qstar |
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