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sonjalin

02-06-2012 10:31 AM

LC-MS (why analytes must be in ionic form?)

I was told when running LC before MS analysis, pH of the solvents / eluents must be adjusted in such a way that the analytes will be in ionic form. But why, if they will be ionized after LC run?

Selina

03-16-2012 02:49 AM

Re: LC-MS (why analytes must be in ionic form?)

Have you tried any run with adjusting the pH and without adjusting the pH of the solvents?

Is there any differences in the performance?

Selina

03-21-2012 07:38 AM

Re: LC-MS (why analytes must be in ionic form?)

Quote:

Originally Posted by Selina (Post 439124)

Have you tried any run with adjusting the pH and without adjusting the pH of the solvents?

Is there any differences in the performance?

May Be u can Try.

Thank You.

pigfarmer

06-21-2012 06:09 PM

Re: LC-MS (why analytes must be in ionic form?)

Quote:

Originally Posted by sonjalin (Post 438411)

I was told when running LC before MS analysis, pH of the solvents / eluents must be adjusted in such a way that the analytes will be in ionic form. But why, if they will be ionized after LC run?

Um...your question is a circle. You use the solvents to run the LC right?

Hermosaorb

02-11-2013 11:26 AM

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