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Determination of noncovalent binding of peptides (hexamer) by MS

Determination of noncovalent binding of peptides (hexamer) by MS - Mass Spectrometry Forum

Determination of noncovalent binding of peptides (hexamer) by MS - Discuss and post questions about LC-MS, Q-STAR, MALDI-TOF, and other Mass Spectrometry Questions in the Mass Spec Forum.


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Old 02-29-2008, 07:12 AM
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Default Determination of noncovalent binding of peptides (hexamer) by MS



Hi, there

How to determine the noncovalent binding peptides (hexamer of 34mer and 36mer peptides) by using mass spectrometry?

I am working on MS determination of noncovalent binding of peptide (hexamer), but current instruments (MicrOTOF-Q and Autoflex (III) MALDI-TOF/TOF instruments , Bruker Daltonios) can detect monomer and dimer of the peptide, what's problem with the MS parameters? Are these two instruments suitable for detecting hexamer of peptide?

Thanks!

Last edited by txqian; 02-29-2008 at 08:33 AM.
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