| |||||||
| Register | Blogs | FAQ | Members List | Calendar | Science Groups New! | Arcade | Search | Today's Posts | Mark Forums Read |
| Mass Spectrometry Forum Discuss and post questions about LC-MS, Q-STAR, MALDI-TOF, and other Mass Spectrometry Questions in the Mass Spec Forum. |
|
![]() |
| | LinkBack | Thread Tools | Display Modes |
| |||||
| a new member here, want to find some help from experts in this forum. It is about the resolution issue of LTQ mass spectrometry, I use Zoom scan, SIM mode to analyze my sample, usually we can observe isotopic peaks for a protein, but these days, these peaks disappear, the resolution seemed to have a severe drop. what is the most likely problem I have met, sample problem or equipment problem? Thanks in advance! |
| | ||||
| ||||
| |
| |||||
| You could check your helium tank – sounds like it may be out. Other causes of your problem could include electronic failure (although I would expect an “all or nothing” response in this scenario) or perhaps loss of calibration. Hope this helps! |
| |||||
| Thanks a lot, it do helps. Regarding the electronic failure, I observed that all the components and parameters are fine, within the torlance of setting value, so I think it might be ok. I will check the helium tank first. |