| | Re: problem with KO litter survival
Usually we only have one pregnant female in the cage, so when the babies were born, it would just be the pups and the dam. The litter size is usually higher with young female (6wks- 3 mo old) , but the litter size also dropped after its peak of 10-11 pups per litter. Was the dam demonstrating a good maternal behaviour? (sometimes your gene-of-interest may affect the behavior as well, on top of survival) For the females bite the pups and the pups can walk around, you might want to put jelly food at the bottom of the cage and separate the dam and pups, seeing if the pups can survive.