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#2
11-29-2011, 11:24 AM
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 Re: Are knockout mice transgenic mice? I think many people would consider KO-mice to be transgenic. Although the final product doesn't always contain a transgene, a transgenic cassette is always used to generate KOs, it just happens that the cassette is often removed. So I think it would be worth mentioning the aspects of transgenic technology that are used in generating KO alleles in embryonic stem cells.  |
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