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Are knockout mice transgenic mice?
Writing an essay on transgenic mice and wondering if i should talk about knockout mice
Re: Are knockout mice transgenic mice?
I think many people would consider KO-mice to be transgenic. Although the final product doesn't always contain a transgene, a transgenic cassette is always used to generate KOs, it just happens that the cassette is often removed.
So I think it would be worth mentioning the aspects of transgenic technology that are used in generating KO alleles in embryonic stem cells.
|knockout , mice , transgenic|
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