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Where can I find information on producing...
Knockout Mouse Forum
Discuss and post questions about knockout mice, transgenic mice and other transgenic animal models.
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| Assuming you're currently doing a degree I'd guess that your university has got subscriptions to a number of journals. Go to the library and ask at the help desk about finding that information. Personally I always found electronic journals were easier and quicker to search through, and theres a good chance that you'll be able to access these on university computers. |
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| google it. Unlike the previous poster you probably won't find this info in articles unless you already known how to make such a mouse. Journal articles are so short and condensed that only the bare minimum info, not all the backgroudn for the techniques. http://users.rcn.com/jkimball.ma.ult...icAnimals.html http://www.dbc.uci.edu/~tjf/tmf_tgms.html |
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| I second that, gibbie99. I too am new to this, and found that the papers/articles tend to assume that the reader knows the basic stem cell/molecular biology techniques and if you are new to this field, it goes over your head. So googling it is the best way. BTW, those are good sites suggestions. |
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| Knockout/transgenic mice production: for starters see boston-umc transgenic mouse production website: Production of Transgenic Mice check out the sections: Production of Transgenic Mice ----------------Schematic overview ----------------DNA: construction and purification ----------------Identifying Transgenic founders Production of Knockout Mice Also consider buying a book, such as: Manipulating the mouse embryo; Google books preview: Manipulating the Mouse Embryo: : a ... - Google Book Search |
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