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GM-CSF Calculation

GM-CSF Calculation - Immunology and Host-Pathogen Interactions

GM-CSF Calculation -


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Old 01-28-2009, 04:45 AM
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Question GM-CSF Calculation



Hi is it possible to convert the U/mL values for GM-CSF in pg/mL - just as itīs possible for the endotoxin units with 1 EU/mL corresponding about 100pg/mL Endotoxin ?
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Old 01-28-2009, 04:45 AM
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Default Re: GM-CSF Calculation

The entity EU describes the biological activity of an endotoxin and was introduced by the U.S. Food and Drug Administration (FDA).

The biological activity causing pyrogenic effects depends on a variety of factors like polysaccharide chain length, aggregation status, solubility in biological fluids, bacterial source, associated substances, etc.

As an example 100 pg of the standard endotoxin EC-5, 200 pg of EC-2 and 120 pg of endotoxin from Escherichia coli 0111:B4 have an activity of 1 EU.

It is taken as a rule of thumb that 1 EU corresponds to 100 pg of endotoxin
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