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Protein Disulfide Bonds and Fixation of Tissues in Histology?

Protein Disulfide Bonds and Fixation of Tissues in Histology? - Histology Forum

Protein Disulfide Bonds and Fixation of Tissues in Histology? - Histology Forum. Talk, discuss and post questions on general histology methods including tissue processing, embedding tissues, sectioning, special staining, enzyme staining and silver staining of samples.


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Old 07-04-2008, 09:13 AM
Pipette Filler
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Default Protein Disulfide Bonds and Fixation of Tissues in Histology?



Hiya dudes,
a weird question for all those histologists....

during fixation of tissues and cells what exactly happens to intracellular cysteine disulfide bonds with formaldehydes and paraformaldehydes?

Isnt it known that PFAs cross-link proteins? What about formaldehyde?

Do these fixatives stabilize bonds?
thanks
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bonds , disulfide , fixation , histology , protein , tissues


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