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Protein Disulfide Bonds and Fixation of Tissues in Histology?

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Protein Disulfide Bonds and Fixation of Tissues in Histology?

Protein Disulfide Bonds and Fixation of Tissues in Histology? - Histology Forum

Protein Disulfide Bonds and Fixation of Tissues in Histology? - Histology Forum. Talk, discuss and post questions on general histology methods including tissue processing, embedding tissues, sectioning, special staining, enzyme staining and silver staining of samples.

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07-04-2008, 10:13 AM

dave2006

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Protein Disulfide Bonds and Fixation of Tissues in Histology?

Hiya dudes,
a weird question for all those histologists....

during fixation of tissues and cells what exactly happens to intracellular cysteine disulfide bonds with formaldehydes and paraformaldehydes?

Isnt it known that PFAs cross-link proteins? What about formaldehyde?

Do these fixatives stabilize bonds?
thanks

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bonds , disulfide , fixation , histology , protein , tissues

« Choosing Paraffin for Embedding Tissues | Frozen Tissue Section Formalin Fixation »

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Protein Disulfide Bonds and Fixation of Tissues in Histology?

Protein Disulfide Bonds and Fixation of Tissues in Histology? - Histology Forum

Protein Disulfide Bonds and Fixation of Tissues in Histology? - Histology Forum. Talk, discuss and post questions on general histology methods including tissue processing, embedding tissues, sectioning, special staining, enzyme staining and silver staining of samples.