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Difference between Deletion and Deletion with LOH

Difference between Deletion and Deletion with LOH - Genomics Forum

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Old 06-07-2010, 05:48 AM
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Default Difference between Deletion and Deletion with LOH



Hi all

I'm doing copy number and LOH studies on a single SNP-array platform.

Can anyone please tell me the difference between deletion without LOH and
deletion with LOH? What are the possible mechanisms behind these 2 categories?

Thanks a lot!
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Old 02-14-2012, 08:18 PM
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Default Re: Difference between Deletion and Deletion with LOH

deletion can lead to LOH, and can occur at the same time, but LOH does not necessarily mean a deletion is present. there are multiple ways of getting LOH (loss of heterozygosity), and deletion is only one of the many methods

Last edited by admin; 02-15-2012 at 04:04 AM.
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