Go Back   Science Forums Biology Forum Molecular Biology Forum Physics Chemistry Forum > General Science Forums > General Science Questions and Layperson Board
Register Search Today's Posts Mark Forums Read

General Science Questions and Layperson Board General Science Questions and Layperson Board


peptide synthesis without amidation

peptide synthesis without amidation - General Science Questions and Layperson Board

peptide synthesis without amidation - General Science Questions and Layperson Board


Reply
 
LinkBack Thread Tools Display Modes
  #1  
Old 10-27-2012, 10:54 AM
Pipette Filler
Points: 10, Level: 1 Points: 10, Level: 1 Points: 10, Level: 1
Activity: 0% Activity: 0% Activity: 0%
 
Join Date: Oct 2012
Posts: 2
Thanks: 0
Thanked 0 Times in 0 Posts
Default peptide synthesis without amidation



hello

i am using fmoc strategie for the synthesis of small peptides. The problem is that the cleavage from the rink-amide resing gives a peptide with an amidation on the c-terminus. For my next peptides i need a free c-terminus without this amidation. So I tried to find a linker which allows the synthesis of this kind of peptides but wasn't successfull. Is there anybody who knows a linker-system to overcome this problem. Preferably using fmoc strategie further on. Or is there a reaction wich allows me to cut of only the c-terminal amidation afterwards?

best regards
christian
Reply With Quote
Reply

Tags
amidation , peptide , synthesis


Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Trackbacks are On
Pingbacks are On
Refbacks are On

Forum Jump

Similar Threads
Thread Thread Starter Forum Replies Last Post
What are the different techniques are there in peptide synthesis such N- Kaushil Peptide Forum 1 09-01-2009 12:33 PM
Custom Peptide Synthesis Company sinopep03 Peptide Forum 0 01-04-2009 02:15 AM
96 well plate peptide synthesis service glbiochem Chit Chat 0 11-15-2007 05:22 AM
Custom Gene Synthesis or Peptide Synthesis biomatik Molecular Biology Products and Vendors 0 10-05-2007 03:54 PM


All times are GMT. The time now is 04:49 PM.


Powered by vBulletin® Version 3.8.4
Copyright ©2000 - 2014, Jelsoft Enterprises Ltd.
Copyright 2005 - 2012 Molecular Station | All Rights Reserved
Page generated in 0.11179 seconds with 16 queries