Lost In The Labyrinth: Decoding The Instructions That Tell Cells How To Become Blood

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Blood cells have limited lifespans, which means that they must be continually replaced by calling up reserves, and turning these into the blood cell types needed by the body. Claus Nerlov and his colleagues at the European Molecular Biology Laboratory unit in Monterotondo, Italy, in collaboration with researchers from Sten Eirik Jacobsen's laboratory at the University of Lund in Sweden, have now uncovered how an intracellular communication pathway contributes to this process.