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Gene Therapy Discuss gene therapy issues, methods and protocols for viral gene therapy, problems and solutions.


First Human Gene Therapy

First Human Gene Therapy - Gene Therapy

First Human Gene Therapy - Discuss gene therapy issues, methods and protocols for viral gene therapy, problems and solutions.


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  #1  
Old 09-05-2008, 05:48 AM
Pipette Filler
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Default First Human Gene Therapy



On September 14, 1990 at the U.S. National Institutes of Health W. French Anderson, M.D., and his colleagues R. Michael Blaese, M.D., C. Bouzaid, M.D., and Kenneth Culver, M.D., performed the first approved gene therapy procedure on four-year old Ashanthi DeSilva. Born with a rare genetic disease called severe combined immunodeficiency (SCID), she lacked a healthy immune system, and was vulnerable to every passing germ or infection. Children with this illness usually develop overwhelming infections and rarely survive to adulthood; a common childhood illness like chickenpox is life-threatening. Ashanthi led a cloistered existence -- avoiding contact with people outside her family, remaining in the sterile environment of her home, and battling frequent illnesses with massive amounts of antibiotics.

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Old 06-23-2009, 09:15 AM
Pipette Filler
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Default Re: First Human Gene Therapy

Gene therapy is the insertion of genes into an individual's cells and tissues to treat a disease, such as a hereditary disease in which a deleterious mutant allele is replaced with a functional one. Although the technology is still in its infancy, it has been used with some success. Antisense therapy is not strictly a form of gene therapy, but is a genetically-mediated therapy and is often considered together with other methods.
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Old 12-07-2012, 10:59 AM
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Default Re: First Human Gene Therapy

hii....
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Old 01-03-2013, 11:01 AM
Pipette Filler
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Default Re: First Human Gene Therapy

Thank you ! Gene therapy will work, or for what diseases. If gene therapy is successful, it could work by preventing a protein from doing something that causes harm, restoring the normal function of a protein.
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