Gene Therapy Question - Eukaryotic Vectors

[moleculardude]

Hi,
I got a good question:


I would like to introduce myself as MSc student of cell & molecular biology.
I decide to do my master thesis on eukaryotic vector Drawing for human cells.
some question:
what are qualities of perfect eukaryotic vector for gene therapy?
how can we improve these qualities?

Thank you in advance for your help and waiting to hear from you

[kanzure]

Originally Posted by moleculardude

What are qualities of perfect eukaryotic vector for gene therapy

I would think that the "Perfect" eukaryotic vector would be one that (1) can be targetted to specific cells, (2) does not lose information upon infection, and (3) can be controlled by external means (say, electromagnets or compounds released into the blood stream). And most importantly (4) actually work.

Is this what you mean? Different applications of gene therapy would use different gene transplant vectors, undoubtedly.

- Bryan

[admin]

That is a great response Bryan,

I would also incorporate minimal risk and harm to the patient

i.e does the vector incorporate into the patients DNA? If so where? Is that region a minimal risk region?

Also, ideally the vector should be cheap and easy to produce (we hope!).

cheers