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| One in ten women in the Western world get breast cancer; half die from it. How tumours look tells oncologists little about which ones might spread. We want to use mass spectrometry to investigate the composition of blood serum to find markers that allow to diagnose early the onset of this malignant disease and to distinguish different forms to allow tailored treatment. Our group is composed of nearly ten people combining biochemistry, molecular biology, mass spectrometry, chemistry, and programming. We have state-of-the-art instrumentation and have just finished the creation of software that allows extracting peaks from complex mass spectrometric data sets. This forms the foundation of a statistics project to find significant changes in data sets from patients when compared to controls. The ideal candidate would already have or strongly desire knowledge in statistical methods such as Bayesian theory, Principal Component Analysis, Genetic Algorithms, Neural networks and of statistical software like R. or Weka. Samples and medical expertise are obtained through close collaboration with the IEO, Italy's largest private cancer hospital, and INT, Italy's largest public cancer hospital, both situated nearby and having together over 25.000 patients per year. We are a very motivated and mostly young, mixed gender group and would like to encourage applications from women and from out-side Italy. Knowledge of English is expected; Italian is not required. Depending on the experience of the applicant the position can yield into a Ph.D. degree (17.000 Euro/year) or postdoctoral appointment (20.000-27.000 Euro/year). Taxation is 20%; health insurance is included (public). Applications should be in English and contain as PDF or RTF a curriculum vitae, a motivation letter including experience in the field, and the contact details of two references. Application deadline is May 28th, 2004. The data is waiting, so we would like to fill the position as soon as possible. Contact: Dr. Juri Rappsilber, email: [Only registered users see links. ], Further information on the group [Only registered users see links. ], institute [Only registered users see links. ], and hospitals: [Only registered users see links. ], [Only registered users see links. ] |
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| diagnosis , molecular , position |
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