What is siRNA gene silencing and what does it do?

Thanks,
Ikie

i know that andrew fire and craig mello discovered that dsRNA cause RNA interference but they could not deduce RNAi Pathway.( involving Dicer, RISC complex etc)

1) Can u please tell me who / which group/s deduced the RNAi pathway ( for bith si RNA and mi RNA)??

2) or can u plese type link/ site for RNAi PATHWAY discovery (that includes scientists name and their experiments to deduce the pathway)???

3) or can u type the site where i can freely download/ view the total and original paper/s of the scientists who discovered the pathway??


HELP PLEEEEEEASE!!!!!!!!!!!!!!!!!!!!!! thank u!!

i know that andrew fire and craig mello discovered that dsRNA cause RNA interference but they could not deduce RNAi Pathway.( involving Dicer, RISC complex etc)

1) Can u please tell me who / which group/s deduced the RNAi pathway ( for bith si RNA and mi RNA)??

2) or can u plese type link/ site for RNAi PATHWAY discovery (that includes scientists name and their experiments to deduce the pathway)???

3) or can u type the site where i can freely download/ view the total and original paper/s of the scientists who discovered the pathway??


HELP PLEEEEEEASE!!!!!!!!!!!!!!!!!!!!!! thank u!!

Is RNAi related with the presence of multiple copy number of T-DNA in transgenic plants? can a single stranded RNA induce RNAi?
anwers are much appreciated

will...? prevent mRNA from the disease gene from being made into protein.
chew up the gene in the chromosome.
stop the disease proteins from leaving the cell.
turn into a virus that attacks cancer cells.