Hi people! This is my first time using this forum. I am currently a student in high school who is really interested in biology. I am enrolled in a class where the students research a branch of science and conduct experiments with their mentors.
I am researching epigenetics/telomeres. For this upcoming science competition, I have created a research proposal. However, I don't know if it is doable.
My question for you guys is: Is artificially/forcefully methylating a specific DNA sequence in humans possible? I have searched the Internet, and came across DNA methyltransferase, which includes DNMT1, as well as DAM methylase. Each of these enzymes is responsible for the addition of a methyl group to a specific nucleotide in a given gene sequence. Could these enzymes be used in any way to methylate a specific gene? If not, please enlighten me with techniques to accomplish this. The proposal for the competition is due soon and I also have midterms to worry about, so any information would take off a lot of stress.
Thank you all so much.