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| Epigenetics Forum: DNA Methylation, Histone and Chromatin Study An Epigenetics Forum Dealing with DNA Methylation, the study of histones and chromatin |
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#1
03-30-2011, 07:09 PM
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 A screening tool to test reagents that change DNA methylation Dear Friends, I am wondering if there is a tool to screen reagents for their abilities to alter epigenetics (e.g. DNA methylation). Do you think a fully methylated promoter driving a reporter gene would (partially) fit this role? i.e. the reporter won't express if the testing compound does not induce promoter hypomethylation; expression increased when compound cause hypomethylation on the promoter. All comments and ideas are welcome! Thank you!  |
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| change , dna , methylation , reagents , screening , test , tool |
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