[Drosophila] Confused about translocation T(2;4)

Karmella--

T(2;4)ast[v] consists of two parts. One "half" of the translocation
has the second chromosome centromere and the other has the fourth
chromosome centromere. Shown pictorially, the two chromosomes are

2Lt--------21E2|101--------4cen----4Lt

4Rt------101|21E3-------2cen-----------2Rt

Where "2Lt" denotes the telomere of 2L, "4Rt" denotes the telomere of
4R, etc. (Believe it or not, there really is a tiny left arm of the
4th chromosome!) Each "half" of a translocation is called a
translocation segregant and the "halves" of T(2;4)ast[v] shown above
are called Ts(2Lt;4Lt)ast[v] and Ts(2Rt;4Rt)ast[v], respectively.

In the stock, Ts(2Rt;4Rt)ast[v] segregates from the In(2L)Cy,
In(2R)Cy, al[2] Cy[1] L[4] sp[2] chromosome and
Ts(2Lt;4Lt)ast[v] segregates from a normal 4th chromosome, based on
the homology of the centromeric regions. The stock genotype could be
rewritten as

Ts(2Rt;4Rt)ast[v]/In(2L)Cy, In(2R)Cy, al[2] Cy[1] L[4] sp[2];
Ts(2Lt;4Lt)ast[v]/+

Hope this helps,
Kevin

__________________________________________________ ________
Kevin Cook, Ph.D. Bloomington Drosophila Stock Center
Department of Biology [Only registered users see links. ]
Jordan Hall 142
Indiana University 812-856-1213
1001 E. Third St. 812-855-2577 (fax)
Bloomington, IN 47405-7005 [Only registered users see links. ]