Fluorescence And Enzyme & Binding Assays Training Courses

[aftabac]

FLUORESCENCE AND ENZYME & BINDING ASSAYS TRAINING COURSES

21-23 JANUARY

PALM SPRINGS, CA, USA

For full details visit

[Only registered users see links. ]

Select Biosciences welcomes you to attend training courses run by
John C. Owicki PhD, to be held at the Wyndham Hotel, Palm Springs.
Dr. Owicki became a consultant in 1999 and is the author of 70
patents and technical papers. He is also on the editorial board of
the Journal of Fluorescence.

FULL TUTOR BIOGRAPHY:
[Only registered users see links. ]

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FLUORESCENCE ASSAYS IN DRUG DISCOVERY
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What you could gain by attending:

* Master the basic concepts of fluorescence at the level required to

understand fluorometric assays and instrumentation.
* Become familiar with the application of fluorometric assays to the

major classes of pharmacological targets.
* Understand the basis and applications of advanced methods such as
fluorescence imaging, fluorescence population, time-resolved energy
transfer, and fluorescence-fluctuation spectroscopy.
* Learn the important types of interferences in fluorometric assays.
* Discover where to find more advanced information, using the
extensive list of references provided.


Topics include:

* Fluorescence fundamentals
* Labels and labeling chemistries
* Instrumentation
* Interferences and limitations
* Survey of principal fluorescence methods
* Biochemical and cellular applications


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ENZYME AND BINDING ASSAYS IN DRUG DISCOVERY
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What you could gain by attending:

* Master the basic concepts underlying enzyme and binding assays
* Learn how applications in drug discovery sometimes dictate assay
optimization and interpretation which differ from textbook
recommendations.
* Learn how best to extract the information you need from your assays.




Topics include:

* Enzyme kinetics
* Enzyme inhibition: Competitive, noncompetitive, uncompetitive,
irreversible, and promiscuous
* Multiple-substrate enzymes
* Binding equilibria and kinetics
* Deviations from classical textbook behavior
* Optimizing enzyme and binding assays for primary vs. secondary
screening
* Understanding mechanisms and extracting information from your data
* Discussion of commercial data-analysis and simulation software
* Case studies, including receptor binding, kinases, and proteases


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REGISTRATION IS AVAILABLE ONLINE
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[Only registered users see links. ]

We look forward to seeing you there.


best regards
aftab ahmad